Study Overview

The placenta is an organ that develops in your uterus during pregnancy.  It connects you and your baby through the umbilical cord. It provides the oxygen and nutrients that your baby needs to grow.
 
Substances used during pregnancy may change the way that the placenta develops. Some substances can cause the placenta to be small. Some can cause the placenta to have fewer blood vessels. Some can change the way that nutrients or oxygen are delivered to your baby.
 
For many substances we don’t know if they cause changes. We also don’t know if any of these possible changes to the placenta will affect the way your baby develops.

The substances we want to study include:

• Opioids – such as oxycodone, fentanyl, Vicodin, and morphine

• Opioid agonist therapies- such as methadone and buprenorphine

• Cannabis- all forms including smoking, vaping, ingesting, etc.

• Nicotine– all forms including smoking, vaping and nicotine replacement therapies

We are interested in examining the effects of these substances when used by themselves during pregnancy, when multiple types of substances are used during pregnancy, and when no substances are used during pregnancy.

This study has been developed in collaboration with peer researchers who have lived experience of substance use in pregnancy. Our goal is to approach this work in an empathetic, non-judgmental, trauma informed, and anti-oppressive way. Ultimately, we wish to support people in their choices and lives. Our peer researchers have reviewed and will review every step of the project, ensuring that our approach and methods are appropriate. They will review all results before anything is presented or published. They will ensure that results are presented sensitively and in a manner that is relevant to the study participants.